Phenylephrine is not safe for consumption by pregnant women, especially in the first trimester of their pregnancy. It might feel convenient to take a decongestant in case of a cold or allergy, but it could have adverse effects on your babys development. Extended release: Take 120 mg every 12 hours or 240 mg every 24 hours. All rights reserved. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Decongestants: Pseudoephedrine and phenylephrine (Sudafed, DayQuil, Claritin-D), especially if taken during the first trimester, may cause stomach defects or affect blood flowto the placenta though some doctors will recommend in limited amounts in the second and third trimesters. Spray Sudafed PE is believed to be safer than the ingested form since it does not affect either the uterus or the future wellbeing of the yet unborn baby. How Climate Change Is Affecting Pregnancy. Placental transfer is likely with phenylephrine's low molecular weight (about 167).AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. This formula has 10% alcohol, phenylephrine, acetaminophen and whatever is in Vicks vapocool. Stop using phenylephrine ophthalmic and call your doctor at once if you have: fast or irregular heart rate; sweating, tremors; pale skin, light-headed feeling; severe headache, buzzing in your ears, anxiety, shortness of breath; or chest pain or pressure, pain spreading to your jaw or shoulder. Create an account to follow your favorite communities and start taking part in conversations. Anyone experiencing side effects or possible interaction between a nasal decongestant and their regular medication should speak with a healthcare professional. The symptoms that phenylephrine tends to deal with are nasal congestion and breathing. PHYSICIANS SHOULD COMPLETELY FAMILIARIZE THEMSELVES WITH THE COMPLETE CONTENTS OF THIS LEAFLET BEFORE PRESCRIBING PHENYLEPHRINE HYDROCHLORIDE OPHTHALMIC SOLUTION. Accessed July 15, 2022. In others, it is only available via prescription. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Guide to a Healthy Pregnancy, Birth control pills - Harmful in early pregnancy. Such side effects may include vomiting, temperature increase, and even coma, all of which you should seek emergency medical attention. The FDA categorizes medications based on safety for use during pregnancy. Phenylephrine is a decongestant.. Acetaminophen, diphenhydramine, and phenylephrine is a combination medicine used to treat cold and flu symptoms such as runny or stuffy nose, sneezing, cough, sore throat, headache, fever, and body aches.. Phenylephrine is both an over-the-counter and a prescription medication. For these, please consult a doctor (virtually or in person). Do not drive or operate heavy machinery until you know how phenylephrine affects you. Take this medication exactly as prescribed by your doctor. Animal studies are not available for the combination product. The dose may be repeated every 3 to 5 minutes up to a maximum of 3 drops in each eye. For potential or actual medical emergencies, immediately call 911 or your local emergency service. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. Decongestants are some of the most commonly used drugs, however, so fully understanding the consequences of taking them during pregnancy is important, said Mitchell, director of the Slone Epidemiology Center at Boston University. information submitted for this request. Phenylephrine may be found in some form under the following brand names: Serious side effects have been reported with phenylephrine. Pseudoephedrine and phenylephrine are available as oral tablets and liquids, while the latter is also available as a direct-acting nasal spray. I think you can take pseudoephedrine which is actually sudafed before all the meth stuff. What Pregnant People Need to Know About COVID-19, Pregnancy Pampering: What's Safe, What's Not, Relieving Cold Symptoms Without Toddler Cough Suppressants, COVID-19 Vaccine During Pregnancy: Everything Parents Should Know, The Best Allergy Medicines and Treatments for Kids. Progestin-only pills (POPs) for contraception. WebBackground: Fenfluramine was withdrawn from the U.S. market in 1997 because of its association with cardiac-valve abnormalities in adults. Take one tablet every 4 hours when needed. I accidentally used phenylephrine hcl 0.25% hemorrhoid gel on my back (instead of hydrocortisone 1%). Philadelphia, PA: Wolters Kluwer Health (2015): "Product Information. Phenylephrine Hydrochloride (phenylephrine)." What will happen to my baby if i took a cough remedy containing phenylephrine while pregnant? In the meantime, use another method of birth control, such as condoms. It is usually administered by a healthcare provider immediately prior to eye examinations or procedures. But for the first time, the authors found links between first-trimester use of pseudoephedrine (also in Sudafed) and a 3-fold higher risk of so-called limb reduction defects. Medically reviewed by Drugs.com. (2019). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To tackle cold-like symptoms, you can increase fluid intake, increase resting time, take warm baths and even use humidifiers. An older study from 2003 investigated the effect of pseudoephedrine on milk production and the infants exposure through breast milk. When ingested, phenylephrine may not only narrow the blood vessels inside the nasal cavity but can also do the same to the blood vessels inside the uterine wall. Never use this subreddit as your first and final source of information regarding your question. PromethazinePhenothiazines, such as promethazine (contained in some of these combination medicines [e.g., Phenergan-D]), have been shown to cause Image: Shutterstock Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. WebIm 13 weeks. Use these dosage charts for infants and children under 12 years old: The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Pseudoephedrine and phenylephrine are common ingredients in medicines for the common cold, flu, and allergies. It is not known if phenylephrine crosses into human milk. nervousness. Webpharmacist before taking any NSAIDs during pregnancy.3,4 What can I take for allergies and hayfever? Intermittent use doesn't hur You should be fine, but you should check with the pharmacist or your. If phenylephrine is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. Even so, some people may believe non-ingested Sudafed PE may not be detrimental to a pregnant woman and the unborn child. First-trimester use of phenylephrine, which is found in Sudafed among other products, was tied to an eight-fold higher risk of a heart defect called endocardial cushion defect. Nurses had interviewed the mothers of babies with birth defects not caused by chromosome problems, and Mitchells group analyzed the results for a total of 12,700 infants, comparing them to answers from the mothers of 7,600 infants without deformities. If you feel bad don't take it again but other than that don't worry :). he said he can't condone alcohol use so not to get him wrong but its ok as long as I don't take it all the time. Could a monthly antibody injection be a promising endometriosis treatment? Eventually, that reduces the conditions to allow for normal breathing. People who are pregnant or breastfeeding should speak with a doctor before taking nasal decongestants. a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), oxytocic drugs such as oxytocin (Pitocin), tricyclic antidepressants such as trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil), and clomipramine (Anafranil), angiotensin-converting enzyme (ACE) blockers such as benazepril (Lotensin, Lotensin HCT), captopril (Capoten, Capozide), enalapril (Vasotec, Vaseretic), fosinopril (Monopril, Monopril HCT), lisinopril (Prinivil, Prinzide, Zestril, Zestoretic), moexipril (Univasc, Uniretic), quinapril (Accupril, Accuretic, Quinaretic), ramipril (Altace), and trandolapril (Mavik, Tarka), angiotensin receptor II blockers such as azilsartan (Edarbi), candesartan (, norepinephrine transporter inhibitors, such as atomoxetine (Strattera), ergot alkaloids, such as methylergonovine maleate, -adrenergic antagonists such as doxazosin (Cardura) and prazosin (Minipress), phosphodiesterase type 5 inhibitors such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Cialis), vardenafil (Levitra), certain medications for high blood pressure such as carvedilol (Coreg) and labetalol, calcium channel blockers, such as nifedipine (Adalat, Nifedical, Procardia), amlodipine (Norvasc), verapamil (Calan, Isoptin, Covera, Verelan), and diltiazem (Cardizem). Even the eight-fold increase in risk indicated by the study results, while it sounds large, would translate to a 2.7 in 1,000 chance the baby would have the defect, he said. Since pseudoephedrine and phenylephrine belong to the same medication class, they can cause similar side effects. The phenylephrine in Sudafed PE may have several listed side effects. A doctor may prescribe a short course of intranasal corticosteroids to help alleviate the condition and manage withdrawal symptoms. Didn't find any significant interactions. MNT is the registered trade mark of Healthline Media. His team worked with a large collection of data on babies born with birth defects between 1993 and 2010. Possibility of causing congenital disabilities. Phenylephrine: A monitoring study including 1249 mother-child pairs that had first trimester phenylephrine exposure showed an increase in malformation, with association greater with minor defects than major defects (8 eye and ear defects, 6 syndactyly, 4 preauricular skin tags, and 3 clubfoot cases); 4149 any time pregnancy exposures were associated with 15 congenital dislocation of the hip, 6 umbilical hernia, and 4 other musculoskeletal defects. include protected health information. SOURCE: bit.ly/17mAbMT American Journal of Epidemiology, online July 3, 2013. The maximum recommended dose is 200 mcg for bolus injection and 200 mcg/min for infusion. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. These may include: Some people may experience additional side effects when using pseudoephedrine, including: Anyone experiencing serious side effects from a nasal decongestant should seek urgent medical advice. 16th ed. -Routine use of acetaminophen during pregnancy is not advised. They also reduce the risk of a fertilized egg implanting outside the uterus (ectopic pregnancy). As such, people need to check the medication label to find out the exact dose of each ingredient. Doctors refer to this as rhinitis medicamentosa, or rebound congestion. Nasal decongestants can cause some general side effects, the most common of which is insomnia. Recent findings show that the use of a decongestant during the first trimester of pregnancy may raise the risk of certain rare birth defects in your unborn child. I am sure everything is fine since you only took it one time. Follow the directions on your prescription label carefully. Your doctor and you will decide if the benefits outweigh the risk of using phenylephrine. Label: 4 way fast acting phenylephrine hydrochloride spray [Fact sheet]. Based on Advertising revenue supports our not-for-profit mission. This level means some animal studies suggest fetal risk but no human studies At 33 weeks of pregnancy both medications are fine to take. WebSide effects Pregnancy, breastfeeding and fertility Taking it with other medicines and herbal supplements Common questions Related conditions Allergies Common cold Cough Hay fever Sinusitis (sinus infection) Useful resources HealthUnlocked: Sudafed forum healthunlocked.com Allergy UK: charity www.allergyuk.org The recommended dose of phenylephrine for dilation of the pupil is 1 drop to the affected eye. WebPhenylephrine Usage. If you took a decongestant in the first trimester your child would have about a 2.7 in 1,000 chance of having a defect. We avoid using tertiary references. Medications can interact with certain foods. BMJ. Take this medication exactly as prescribed by your doctor. http://www.tga.gov.au/docs/html/medpreg.htm" (2010): Briggs GG, Freeman RK. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Acetaminophen: Routinely used during all stages of pregnancy, it appears safe for short-term use. She went o Dr. Gibson is a pharmacist and medical communicator. The typical low-dose aspirin you can buy without a prescription is 81 mg. Low-dose aspirin is safe to use throughout pregnancy. During the first trimester, higher doses of aspirin may raise Label: Pseudoephedrine HCL tablet, film coated [Fact sheet]. To prevent the condition, doctors and pharmacists recommend avoiding the use of topical nasal decongestants for no more than a few days in a row. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Dr. Gibson is a pharmacist and medical communicator benefits outweigh the risk of using phenylephrine pregnancy! Typical low-dose aspirin you can take pseudoephedrine which is actually Sudafed before all the meth stuff overdose occur! In medicines for the combination product of aspirin may raise label: pseudoephedrine hcl tablet, film coated [ sheet! Sudafed PE may not be detrimental to a pregnant woman and the infants exposure through breast milk into milk... Information on more than 24,000 prescription drugs, over-the-counter medicines and natural products bit.ly/17mAbMT Journal! 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