"There are people that last a long time that are not very great dancers, and there are people that are really good and show improvement that don't wind up sticking around too long," he told The Washington Post. Macchio was born in Huntington, New York. Ralph Macchio, the actor who portrayed Daniel Karate Kid Karate, was born on January 17, 1950 in The Bronx, New York, to Greek and Italian parents. As most fledgling stars, Macchio started his career by lending his skills to commercials, notably one for Bubble Yum gum. How does someone learn karate without training in real life? [9] Macchio's work in the Karate Kid series made him "stratospherically famous". A healthy lifestyle doesnt hurt. More than 6 million individuals worldwide have Parkinson disease. If you have watched Ralph from the beginning, you can tell that the actor has not aged. Unlike their father, they all prefer to stay out of the limelight, with their oldest the only one who has a public Instagram account. Their story is told primarily through their financial situation, which is one of the plot devices. While his hair appeared to be thinning in his 20s and 30s, he sports a thick head of hair in the Cobra Kai series. They both look very young for their age I think Ive just gotten lucky in the gene department. He also names having a healthy and active lifestyle as another reason hes been defying the aging process. So, to prep for the role, he "slept outside one night under newspapers just like Johnny did, and it was not fun.". nota la scena finale di questo film, il duello chitarristico tra Eugene e Jack Butler (impersonato dal guitar hero Steve Vai), un chitarrista rock che ha venduto l'anima al diavolo: Eugene, quasi sconfitto, riesce a prevalere sull'avversario con un brano di stile classico (Eugene's Trick Bag, scritto ed eseguito dallo stesso Steve Vai ed ispirato al Capriccio Op. However, when his wife showed him a photo of a Yorkshire terrier from a shelter onLong Island, New York, where they live (via Newsday), things changed. Reports that used trehalose to counteract the neurotoxicity in PD are discussed, focusing particularly on the autophagy promoting, protein stabilization, and antineuroinflammatory effects oftrehalose. And, as his time with the franchise progressed, he gained even more experience. View 3 excerpts, references background and results, By clicking accept or continuing to use the site, you agree to the terms outlined in our. (Another fun fact to note is that, originally, the character was namedDaniel Webber (via Screen Rant), but, when the actor was cast, the last name was changed to make it sound Italian-American, like the actor himself.). In his most notable role to date, as the protagonist in The Karate Kid, Macchio was 24 when he played 17-year-old high school student Daniel LaRusso . In fact, , who has some acting credits, appeared in Season 4 of the reboot, playing Vanessa, one of Daniels cousins . I think I've just gotten lucky in the gene department." [28] They married on April 5, 1987, and have two children, Julia (born 1992) and Daniel (born 1996). He also names having a healthy and active lifestyle as another reason he's been defying the aging process. In celebration of Daniels birthday last October, Julia shared a photo of them together on Instagram along with a heartfelt message.ae0fcc31ae342fd3a1346ebb1f342fcb, Youve been my best friend since the day you were born and one of the greatest joys of my life is getting to be your sister! Julia wrote in the caption. But now he's proud of it," he told The Guardian. (Check out this throwback photo from the early days of their courtship that their daughter posted on Instagram.) He played the role of Daniel LaRusso, a teen fighting champion who was a small-town outsider in the film trilogy The Karate Kid. This is demonstrated by Macchios journey. He began tap dancing lessons at the age of 3 which would help him later in life when he competed on a certain reality TV dance competition and was discovered on stage at a dance recital when he was 16 . Hes credited his youthful good looks to good genetics, since both his parents look younger than they are. [7], Macchio appeared in the 1986 film Crossroads, portraying music student Eugene Martone. good money making methods skyblock; religious habit supply; palm beach lakes high school news; hoops bar and grill menu louisville, ky; dtv gov maps. Stellantis hesam1981. He and partner Karina Smirnoff came in a very respectable fourth place, with Macchio turning in a series of entertaining, confident, and downright graceful performancesalbeit none quite as elegant or acrobatic as that signature crane move from The Karate Kid. The Karate Kid, in which he starred, became a worldwide phenomenon in 1979. The Outsiders: Directed by Francis Ford Coppola. In vitro data fail to indicate a central role for Bax in apoptotic death of DA neurons in an experimental Parkinson's disease paradigm, but in vitro data suggest that in the human pathology, Bax may be a cofactor in caspase activation. Ralph has a younger brother Steven. Joining the hit show in its final season, he playedJeremy Andretti (another character whose last name is Italian-American, like the actor) for 21 episodes (via Vanity Fair). [17], In April 2012, Macchio was cast in the film Hitchcock, based on the non-fiction book Alfred Hitchcock and the Making of Psycho. The first time a talent agency met Ralph Macchio, a well-known actor and producer, he was 16 years old. When he was asked in an interview, at 18, if it bothered him that he looked 15 or 14, he said, As far as business wise, its been the best thing I could ask for. It seems like Macchio was predicting the future, because, just a few years later, his youthful appearance would lead him to play the part that would take his career to a level he probably never could have imagined. Ralph Macchio played Carl Morelli, the main character who narrates his own life story about growing up in a New York City studio apartment with his sprawling Italian-American family. He suffered injuries to his knee and calf that kept him from scoring in the first half of his performance, resulting in a 46 percent field goal percentage. sean penn parkinson's disease; mockingbirds attacking my cat; a level geography independent investigation examples; rebecca rogers teacher podcast; Actualits. Ralph Macchio is an American actor who is best known for his role as Daniel LaRusso in The Karate Kid film series. The first time a talent agency met Ralph Macchio, a well-known actor and producer, he was 16 years old. READ: Mike Tindalls reassuring words for Meghan Markle revealed, In honor of their most recent birthday, the Back to the Future actor paid tribute to them. His youthful looks have always allowed him to play the roles of significantly younger characters, even a decade after his teenage years had passed. In "The Karate Kid," Ralph Macchio's character, Daniel LaRusso, gets beaten up by a gang after school, and, to defend himself, enlists the aid of a karate sensei for a crash course in the sport. Background: The role of the gut-brain axis has been recently highlighted as a major contributor to Parkinson's disease (PD) physiopathology, with numerous studies investigating bidirectional transmission of pathological protein aggregates, such as -synuclein (Syn). Macchio was also bothered by what he saw as an apparent unfairness in the series' judging system. When he was 17, Macchio landed his first movie role in the 1980 comedy Up the Academy. After the film, he did an interview where he described its premise. As well as so many others." During that time, he was interviewed on "The View" and gushed about how proud he was of her perseverance in the face of adversity. Macchio was already a Broadway alum thanks to some traditional singing and dancing experience in his youth, but in 2016 he returned to the stage for a serious role: the lead in A Room of My Own, a semi-autobiographical comedy by Charles Messina. Macchio began tap dancing lessons at the age of three and was discovered by a talent agent when he was 16 years old. He appeared in the YouTube reboot of Karate Kid, Karate Kid: Cobra Kai, in 2018. When he was 17, Macchio landed his first movie role in the 1980 comedy "Up the Academy." I just did what was necessary," he said inan interview with Leta Powell Drake at the time. It's only natural that the ageless actor is asked about the secrets to retaining his same boyish looks all these years later. Director John G. Avildsen Writer Robert Mark Kamen Stars Ralph Macchio Pat Morita Elisabeth Shue See production, box office & company info Watch on AMC+ with Prime Video Channels More watch options Add to Watchlist 393 User reviews 118 Critic reviews 60 Metascore The role of the gut-brain axis has been recently highlighted as a major contributor to Parkinson's disease (PD) physiopathology, with numerous studies investigating bidirectional transmission of pathological protein aggregates . While the procedure could have helped his hair get a little thicker, the thickness of his hair seems beyond the scope of hair transplant, even by the best a celebritys status and income could afford. BACKGROUND Parkinson's disease (PD) is a neurodegenerative disorder associated with caregiver burden. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. A martial arts master agrees to teach karate to a bullied teenager. Nella commedia Billy Gambini, che viene ingiustamente accusato di omicidio e difeso vittoriosamente dal cugino Vincenzo (Joe Pesci), avvocato alla sua prima causa e dai modi grotteschi. METHODS There was a chunk of time when my son was like, Did you have to? But now hes proud of it, he told The Guardian. Parkinson's disease (PD) is a neurodegenerative disorder associated with caregiver burden. Recommended Reading: Can You Slow Down Parkinsons. Ralph Macchio also has an extra high forehead. It has long been characterised by the classical motor features of parkinsonism associated with Lewy bodies and loss of dopaminergic neurons in the substantia nigra. I also exercise regularly and enjoy playing tennis and softballanything cardio, he told Stack. Nel 1983 ha debuttato nel film diretto da Francis Ford Coppola I ragazzi della 56 strada, con Patrick Swayze, Matt Dillon, Emilio Estevez, C. Thomas Howell, Rob Lowe e Tom Cruise. Macchio has not confirmed whether or not he has scoliosis, but many fans believe that he does based on his appearance. He has appeared in two successful film franchise films, starring in the Karate Kid film series and the sequel television series Braka Kai. Because no one else has access to YouTube Red, the first season of The Last Jedi received a lot of praise and low ratings. What Are The Beginning Signs Of Parkinsons Disease, Latest News On Parkinsons Disease Treatment, Can You Still Drive With Parkinsons Disease. Macchio is known for his youthful looks, which has helped him to continue to be cast in roles that are youthful in nature. There is no certain answer to this question, as Ralph Macchio himself has never given a clear explanation. Despite being diagnosed with Parkinson's disease in 1998, . In an interview with his co-star both then and now, William Zabka, who plays Daniel's nemesis, Johnny Lawrence, Macchio said, "We both said 'no' for decades to everybody having what they thought was their brilliant idea. The actor has been married to his high school sweetheart, Phyllis Fierro, since 1987, giving Hollywood couples major relationship goals. Dancing with the Stars boasts a roster of celebs every year that includes actors, singers, comedians, musicians, entrepreneurs, athletes, reality stars, journalists, internet personalities, newsmakers, and where-are-they-now personalitiesand considering Ralph Macchios well-established place in that last category, its no surprise that he was tapped to appear. The rivalry between two gangs, the poor Greasers and the rich Socs, only heats up when one gang member kills a member of the other. Nel 2018 Macchio ha interpretato di nuovo Daniel LaRusso nella serie TV Cobra Kai, il sequel della trilogia di Karate Kid. A wannabe blues-guitar virtuoso seeks a long-lost song by legendary musician Roberto Johnson. The 1947 Super DeLuxe convertible from The Karate Kid films was given as a present to Macchio. On September 13, 2019, Macchio was rushed to the hospital after suffering a heart attack. Ralph George Macchio Jr. (/mtio/ MAH-chee-oh; born November 4, 1961) is an American actor. Higher rates of burden are associated with adverse outcomes for caregivers and patients. In fact, when the movie celebrated its 30th anniversary, he took to Twitter to thank LaRusso, saying, "You have enhanced my life, dude! 1-5. "It's a satire about these four guys thrown into this military school to be disciplined and they kind of discipline the military school," he explained. As luck and his unbridled talent would have it, Macchio scored the coveted role, joining one of the strongest young ensembles at the time, consisting of then-up-and-coming stars like Tom Cruise, Patrick Swayze, Rob Lowe, and Matt Dillon. When asked about the key to their staying power, Macchio revealed it's a deep commitment to one another. Director Walter Hill Writer John Fusco Stars Ralph Macchio Joe Seneca Jami Gertz See production, box office & company info Watch on Crackle Go to crackle.com More watch options Add to Watchlist 107 User reviews 28 Critic reviews 55 Metascore Awards 1 win The main predictors of CB were caregivers' psychological wellbeing, patients' mood and clinical aspects of PD (disability and severity), and HRQoL of patients and caregivers, which underscores the need to consider the impact of PD on caregivers' well-being. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Ralph Macchio jokes that his parents are to blame for his freakishly youthful appearance. Therapeutic anti-inflammatories which prevent DA neurodegeneration in PD, including anti-inflammatory cytokines, morphinan compounds, NADPH oxidase inhibitors, NF-B inhibitors, and 2-AR agonists all function to inhibit the activation of the PHOX in microglial cells. [21] A recurring joke in the sketch is that Macchio is confused for an adolescent. However, the extent and the characteristics of pathology in the enteric nervous system have not been fully investigated. He has also appeared in other films and television shows throughout his career. Also Check: How To Help A Person With Parkinson Disease. 2023 Brandon Orthopedics | All Right Reserved, Raheem Sterling: An English Professional Footballer, The Importance Of Early Detection And Treatment Of Scoliosis, Complex Regional Pain Syndrome: Causes Symptoms And Treatments. Decades after their 1984 All Valley Karate Tournament bout, a middle-aged Daniel LaRusso and Johnny Lawrence find themselves martial-arts rivals again. But I think Ive just gotten lucky in the gene department., The Huntington, New York-native has always looked younger than his years. Macchio portrayed Psycho screenwriter Joseph Stefano. The results showed that higher frailty status and lower levels of optimism among patients were significantly associated with higher levels of overall burden and higher burden related to the restriction of personal time among caregivers. The ad, which aired in 1980, features the then-young talent showcasing his dancing skills on screen. Dont Miss: Tardive Dyskinesia And Parkinsons. [24], Beginning in 2018, Macchio reprised his role as Daniel LaRusso in Cobra Kai, an action comedy-drama series that began on YouTube Red and later moved to Netflix. The character Mr. Miyagi from The Karate Kid has also been regarded as one of Macchios most popular. Abstract. Institute of Human Anatomy, Department of Neuroscience, University of Padova, Padova, Italy. By clicking accept or continuing to use the site, you agree to the terms outlined in our. Privacy Notice Crossroads is a 1986 America musical drama film inspired by the legend of blues musician Robert Johnson.Starring Ralph Macchio, Joe Seneca and Jami Gertz, the film was written by John Fusco and directed by Walter Hill and features an original score by Ry Cooder featuring classical guitar by William Kanengiser and harmonica by Sonny Terry. We've received your submission. 23,001, This story has been shared 16,342 times. He revives the infamous Cobra Kai dojo, to the chagrin of Daniel LaRusso , now a successful car dealer with a family. When it comes to his diet, Macchio is a bit of a health nut. Cobra Kai begins in the fall of 2017, and re-examines the "Miyagi-Verse" narrative from Johnny's point of view, beginning with his decision to reopen the Cobra Kai karate dojo, and the rekindling of his old rivalry with Daniel. He competed on the 12th season of Dancing with the Stars as a professional dancer. On "The Late Show with Stephen Colbert," Macchio explained that the classic car was gifted to him by Columbia Pictures, the studio behind the film, the day "The Karate Kid Part III"was released. It has been 30 years since The Karate Kid Part III, and Ralph Macchio is still alive and kicking. January 22, 2023. Actor Ralph Macchio takes an affectionate look back at making the 1984 film The Karate Kid, the Cobra Kai series & other roles in his film career. The results demonstrate for the first time in a Parkinsons disease animal model that the neuroprotective effects of rapamycin are associated with glial and anti-inflammatory effects. "Listen I blame my parents," he told People. Its really cool, he explained. Macchio has also written two books: Just My Imagination and Its All True. Nel 2010, quasi in concomitanza con l'uscita del remake The Karate Kid - La leggenda continua, ha ironicamente interpretato se stesso in uno sketch realizzato per il noto sito satirico statunitense "Funny or Die", presentando un finto documentario autobiografico intitolato Wax off, fuck off, in cui fa dell'autoironia la sua arma vincente.[3]. For some celebrity kids you probably havent seen in a while, See What Michael Jacksons Three Kids Look Like All Grown Up. Ralph Macchios career took off after The Karate Kid premiered in 1984. However, its potential role in the human pathology remains to be demonstrated. His success as an orange belt demonstrates his dedication to and passion for karate. Many young viewers may not even believe that the Karate Kid actor is already 60 years old. And, even at the start of his career, the actor credited looking young with helping him get ahead in the industry. An actor, producer, director with an extensive list of credits, Ralph Macchio is best known for his celebrated performance as Johnny in Frances Ford Coppola's The Outsiders; the hit film My Cousin Vinny; and most notably for the title role in the popular classic The Karate Kid and its successors. Ralph Macchio began his acting career when he was 16 years old. Ralph Macchio is an American actor who has a net worth of $40 million. Institute of Human Anatomy, Department of Neuroscience, University of . He is estimated to have a net worth of $5 million. [22], In 2013, he appeared in How I Met Your Mother. . It will only be a matter of time before we discover the truth. So did the star have a knowledge of the art of karate at the time he was cast, beating out Charlie Sheen, Nicholas Cage, and Robert Downey, Jr.for the part? When it comes to his diet, Macchio is a bit of a health nut. One health condition that Macchio has been rumored to have is scoliosis. CNS & neurological disorders drug targets, Evidence has been accumulated showing that inflammatory and cell death pathways are altered both in brain and periphery during Parkinson disease (PD). "It's one of the most famous cars in movies, certainly the most famous car in a movie I was in,"he told Motor Trend. It's thanks to its creators, who are all actual loyal and knowledgeable fans of the films. The 1984 film The Karate Kid starred Ralph Macchio as Daniel LaRusso, a high school student. The couple who have been married since 1988 are parents to Sam, 33, twins Aquinnah and Schuyler, 27, and Esme, who is 20. When I did my audition, he just kept giving me more improvisational F bombs to drop I think he liked my sort of New York kinda young energy, he recalled, speaking of the movies director, Robert Downey Sr., father to A-List actor Robert Downey Jr., who, ironically, also auditioned for the lead in The Karate Kid, as Macchio revealed on The Tonight Show Starring Jimmy Fallon., Dont Miss: Mucuna Pruriens Dosage For Parkinsons. Should a similar multifactorial cascade underlie dopaminergic neuron degeneration in PD, then the optimal therapy for this disease may have to rely on a cocktail of agents, each targeting a different critical component of this hypothesized pathogenic cascade. It is here that we have an update on the Cobra Kai. Many people, in fact, are curious to learn whether any of the other members of the Cobra Kai cast hold black belts. Veronica Macchi MD, PhD. Welcome to Brandon Orthopedics! Macchio began his career in 1969, appearing in the film The Wanderers. [1], His work on The Outsiders helped him to win the role of Daniel LaRusso in the blockbuster 1984 film The Karate Kid. When one thinks of the most popular movies of the '80s, "The Karate Kid" is up there as one of the decade's biggest hits. And, now, with the success of "Cobra Kai," Macchio's son and daughter get to watch Daniel's story further unfold, which Macchio, who refers to himself as "a nerd dad," calls "really wonderful" (via People). That's because the actor owns the1947 Fordconvertible his character was given by Mr. Miyagi in the film, part of the famous "wax on, wax off" scenethat goes down in movie history. Dont Miss: Upright Walker For Parkinsons. The actor was even photographed in one for his interview withHemmings Motor News. Also Check: Experimental Treatment For Parkinsons Disease. There is no currently available information to suggest that Ralph Macchio has Parkinsons disease. "People ask me about it all the time." Higher rates of burden are associated with adverse outcomes for caregivers and patients. in A ROOM OF MY OWN", "Ralph Macchio, Elijah Wood Think Bad Thoughts in Indie Music Clip", "Ralph Macchio Plays 'Psycho' Scribe Joe Stefano In 'Hitchcock', "WATCH: 'Cobra Kai' Cast Starred in a 2007 Music Video", "Ralph Macchio on How He Survived Lean Years in His Career: "I Still Live Fairly Modestly", "Ralph Macchio's 50th Birthday: From Karate Kid To Dancing Star", "Ralph Macchio: Celebrity Hockey Captain", "Ralph Macchio gets kicking Islanders bobblehead", "Ralph Macchio Q&A: The story behind 'Wax On, F*ck Off', "Ralph Macchio to guest star on 'Kevin Can Wait', "Watch 'Conan' Producer Jordan Schlansky Get Totally Owned by Childhood Hero Ralph Macchio (Video)", "A cheery revival for 'How to Succeed' Review: Grown-up Ralph Macchio charms as this updated '61 Pulitzer Prize musical opens a national tour here', Ralph Macchio & Yuji Okumoto Present Best Fighting Game at The Game Awards 2020, Ralph Macchio of "Cobra Kai" on Memoir "Waxing On: The Karate Kid and Me", The Karate Kid Part II: The Computer Game, https://en.wikipedia.org/w/index.php?title=Ralph_Macchio&oldid=1140602762, Short description is different from Wikidata, Creative Commons Attribution-ShareAlike License 3.0, Episodes: "Two Guys, a Girl and a Pizza Place" (Parts 1 & 2), Daniel LaRusso, Colonel Steven Shay, Janitor, Voice, episode: "Caffeine-Induced Aneurysm", Episode: "Remake A.K.A. In Macchios late 20s and early 30s, he started to conceal his thinning hair by combing it over to cover the thinning portions. He especially wanted to playJohnny Cade"maybe because he was the sort of runt of the group and Iwas kind of the smallest guy in my class," Macchio shared with Vanity Fair. beating out Charlie Sheen, Nicholas Cage, and Robert Downey, Jr. He is best known for his portrayal of Daniel LaRusso in three Karate Kid films. "My wife and Ilove the name Daniel," he explained. [1] Beginning in October 2008, he appeared in several episodes of the ABC Network television series Ugly Betty as Archie Rodriguez, a local politician who is Hilda's love interest. Another possibility is that he walks with a limp as a result of a neurological condition. [18], Macchio appeared in the 2007 music video for the song "Sweep the Leg" by No More Kings as a caricature of himself and Daniel from The Karate Kid. Mike Tindalls reassuring words for Meghan Markle revealed, Treatment Of Fatigue In Parkinsons Disease, See What Michael Jacksons Three Kids Look Like All Grown Up, Experimental Treatment For Parkinsons Disease, How to watch: Stitt and Hofmeister debate Wednesday, How To Help A Person With Parkinson Disease, American Parkinson Disease Association Charity Rating, Parkinsons Disease Treatment Crossword Clue. So, to prep for the role, he slept outside one night under newspapers just like Johnny did, and it was not fun., On social media, both Julia and Daniel post a lot about their family. Not only did he go on to star in two more installments of the franchise, but now, over 35 years later, he's reprising the role in its reboot "Cobra Kai." Their uneasy reunion accidentally sparks war-haunted violence, and they share a harrowing fight for survival that will either destroy them or unify them forever. Ralph George Macchio was born on November 4, 1961 in Huntington, Long Island, New York. La sua fama legata al ruolo di Daniel LaRusso nella serie di film The Karate Kid in coppia con Pat Morita. "I also exercise regularly and enjoy playing tennis and softballanything cardio," he told Stack. In 2011, he appeared on the hit dancing competition show, Dancing with the Stars. In an interview on "The Tonight Show Starring Jimmy Fallon," the doting dad revealed that his son's moniker was, in fact, inspired by the character. He is the founder and main author of brandonorthopedics.com, a website that offers valuable resources, tips, and advice for patients looking to learn more about orthopedic treatments and physiotherapy. He is worth a total of $3 million. With his revitalized career came major changes in his appearance. This real-world study demonstrates that caregivers of people with APD experience a greater burden than those caring for people with early PD, and emphasizes the need for implementing treatments that reduce caregiver burden in APD. A lot of stretching necessary. How does someone learn karate without training in real life? She was a gymnast at her high school and did not train for martial arts until after graduation. Macchio received glowing reviews for his portrayal of 16-year-old Johnny Cade in the film, The Outsiders. [13] As of November 2008, Macchio was ranked No. Their story is told primarily through their financial situation, which is one of the plot devices. Because of this, fans and hair experts alike are left to speculate. And, although he had never adopted an animal before, once he became smitten with the little guy, named Oliver, who later became part of his family, Macchio's outlook changed. William Zabka, on the other hand, received a second-degree green belt while filming Tang Soo Do. In 2011, he told People Johnny Cade in the sketch is that he does based on his.! Even more experience when asked about the key to their staying power, is... Remains to be cast in roles that are youthful in nature agree the! You Still Drive with Parkinsons disease Treatment, can you Still Drive with Parkinsons disease adverse... My wife and Ilove the name Daniel, '' he told Stack ha interpretato di nuovo Daniel,! More experience the series ' judging system that Macchio has also appeared in the series ' judging system a! Retaining his same boyish looks all these years later his parents look younger than his years Stars Macchio. To continue to be cast in roles that are youthful in nature on his appearance my,. Then-Young talent showcasing his dancing skills on screen did not train for martial arts after. Acting career when he was 16 years old lifestyle as another reason he 's proud of it ''. The role of Daniel LaRusso and Johnny Lawrence find themselves martial-arts rivals.! Reviews for his interview withHemmings Motor News People ask me about it all the time ''! And enjoy playing tennis and softballanything cardio, he started to conceal thinning! 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